Recruitment is currently open for first responders and veterans. The IMPACT research trial offers psychological treatment for Post-Traumatic Stress Disorder.


*The IMPACT trial has temporarily paused community member recruitment. If you register your interest and leave your details a member of the IMPACT trial team will be in contact as soon as recruitment resumes.


The BDNF trial is currently recruiting members of the community with PTSD. The BDNF study combines PTSD Treatment (prolonged exposure therapy) with aerobic exercise or gentle stretching. You can enquire and refer to the BDNF trial page and a team member will be in contact with you.

This IMPACT trial is comparing a novel, transdiagnostic psychological intervention for PTSD known as the Unified Protocol against Prolonged Exposure therapy, the gold standard in PTSD treatment.


Unified Protocol therapy has promise as an effective treatment for those with PTSD by helping individuals build skills in emotion regulation to better manage the emotional impacts of trauma. Prolonged Exposure (PE) is well established as a treatment for supporting people with PTSD by helping individuals process their traumatic memories and reclaim their lives. Learn more about what to expect during Unified Protocol therapy and PE.

Presently, recruitment for the IMPACT trial is open for treatment delivered via videoconferencing )(available to Victorian residents}. We welcome expressions of interest for face-to-face treatment and will resume in our clinic subject to government guidelines.

Register interest

Am I eligible for the IMPACT trial?

To be eligible for the IMPACT Trial, the following criteria need to be met:*


  • Aged 18 or over
  • Have been diagnosed with PTSD or suspect that they have PTSD following a traumatic event
  • Currently reside in Victoria
  • Access to equipment for videoconferencing (ie computer and internet) for Telehealth
  • Able to attend weekly sessions
  • Have good English comprehension


Unfortunately, this trial is not suitable for individuals who have been diagnosed with a current psychotic disorder such as schizophrenia, or bipolar affective disorder or mania, or a severe drug or alcohol use disorder.


Furthermore, this trial is not suitable for people who are unable to guarantee their own current safety (i.e. have active suicidality, deliberate self-harm, or a current victim/survivor of family violence), or the safety of another (e.g., a perpetrator of violence).


*Other inclusion and exclusion criteria apply, which will be advised upon contact and further assessed during an intake process to confirm eligibility.


What will the IMPACT trial involve?

Participation involves:

  • An intake assessment to assess eligibility and presence of PTSD
  • Random allocation into one of two treatment groups:
    • Ten weekly 90 minute sessions of unified protocol.
    • Ten weekly 90 minute sessions of PE .
  • Completing a number of online surveys and clinical interviews throughout the duration of the study.


Eligible participants will receive treatment at no cost.


Please note: Consent for the research team to communicate with participant’s GP is a requirement for entering into this trial. Participants are encouraged to share this website information with thier GP and other health professionals when expressing interest in this research.


For more information about the trial including possible benefits and risks to participation please read our Plain Language Statement.


Download your guide to the step-by-step process of registering for the IMPACT trial below.

Step-by-step process

How do I refer a client to the IMPACT trial?

Referrers are welcome to contact us if they would like to refer a client.


For additional details on how referrers can support their clients access the IMPACT trial at the Phoenix Australia Traumatic Stress Clinic, please read the Frequently Asked Questions document.


Who is conducting the IMPACT trial?

The IMPACT trial is being conducted by Phoenix Australia – Centre for Posttraumatic Mental Health, a national centre of excellence in posttraumatic mental health, affiliated with the University of Melbourne.


This research project has been approved by the Human Research Ethics Committee of The University of Melbourne (ID Number: 1853047.6).

If you would like to participate or find out more, please contact the Phoenix Australia Traumatic Stress Clinic intake line on 1800 514 905 or register your interest below.