This trial is investigating whether aerobic exercise, in combination with psychological treatment, can improve PTSD symptoms.
Prolonged exposure (PE) therapy is the current gold standard treatment for PTSD. The BDNF trial is investigating whether treatment outcomes for PE can be improved by increasing levels of a protein called brain derived neurotrophic factor (BDNF) through aerobic exercise. Eligible participants would receive treatment using PE at no cost, combined with either aerobic exercise or gentle stretching.REGISTER INTEREST
This study is suitable for participants who:*
Are over the age of 18.
Have PTSD following a traumatic event.
Currently live in Victoria.
Have access to equipment for video conferencing (i.e. computer and internet) for telehealth.
Are able to attend weekly sessions.
Have good English comprehension.
Are able to safely engage in aerobic exercise (that is, do not have a health condition such as heart, lung or muscle problems).
*Unfortunately, this trial is not suitable for individuals who have been diagnosed with a current psychotic disorder such as schizophrenia, or bipolar affective disorder or mania, or a severe drug or alcohol use disorder.
Furthermore, this trial is not suitable for people who are unable to guarantee their own current safety (i.e. have active suicidality, deliberate self-harm or a current victim/survivor of family violence), or the safety of another (e.g. a perpetrator of violence).
Eligible participants will receive treatment at no cost.
Please note: Consent for the research team to communicate with participant’s GP is a requirement for entering into this trial. Participants are encouraged to share this website information with their GP and other health professionals when expressing interest in this research.
For more information about the possible benefits and risks of participating in treatment at the Phoenix Australia Traumatic Stress Clinic please read our Plain Language Statement.
Referrers are welcome to contact us if they would like to refer a client.
For additional details on how referrers can support their clients access the BDNF trial at the Phoenix Australia Traumatic Stress Clinic, please see the attached Frequently Asked Questions document.
This trial is being conducted by Professor Kim Felmingham from the Melbourne School of Psychological Sciences, the University of Melbourne, in collaboration with the Phoenix Australia Traumatic Stress Clinic, an initiative of Phoenix Australia – Centre for Posttraumatic Mental Health, the Australian national centre of excellence in posttraumatic mental health, affiliated with the University of Melbourne.
This research project has been approved by the Human Research Ethics Committee of The University of Melbourne (ID Number: 1954422.8).
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